Detalhe da pesquisa
1.
Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis.
Cell
; 185(9): 1521-1538.e18, 2022 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35447071
2.
Drug-induced death signaling strategy rapidly predicts cancer response to chemotherapy.
Cell
; 160(5): 977-989, 2015 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25723171
3.
Relative mitochondrial priming of myeloblasts and normal HSCs determines chemotherapeutic success in AML.
Cell
; 151(2): 344-55, 2012 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23063124
4.
Steroid-free combination of 5-azacytidine and venetoclax for the treatment of multiple myeloma.
Haematologica
; 2024 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38511268
5.
Mitochondrial apoptotic priming is a key determinant of cell fate upon p53 restoration.
Proc Natl Acad Sci U S A
; 118(23)2021 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34074758
6.
Aneuploidy increases resistance to chemotherapeutics by antagonizing cell division.
Proc Natl Acad Sci U S A
; 117(48): 30566-30576, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33203674
7.
Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer.
Nature
; 529(7586): 413-417, 2016 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26735014
8.
Targeted inhibition of PI3Kα/δ is synergistic with BCL-2 blockade in genetically defined subtypes of DLBCL.
Blood
; 133(1): 70-80, 2019 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30322870
9.
Iterative optimization yields Mcl-1-targeting stapled peptides with selective cytotoxicity to Mcl-1-dependent cancer cells.
Proc Natl Acad Sci U S A
; 115(5): E886-E895, 2018 01 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29339518
10.
Engineered protein disaggregases mitigate toxicity of aberrant prion-like fusion proteins underlying sarcoma.
J Biol Chem
; 294(29): 11286-11296, 2019 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31171724
11.
BH3 profiling as pharmacodynamic biomarker for the activity of BH3 mimetics.
Haematologica
; 109(4): 1253-1258, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37881837
12.
Metabolomic and BH3 profiling of esophageal cancers: novel assessment methods for precision therapy.
BMC Gastroenterol
; 18(1): 94, 2018 Jun 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29933761
13.
iBH3: simple, fixable BH3 profiling to determine apoptotic priming in primary tissue by flow cytometry.
Biol Chem
; 397(7): 671-8, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26910743
14.
Correction: Engineered protein disaggregases mitigate toxicity of aberrant prion-like fusion proteins underlying sarcoma.
J Biol Chem
; 294(46): 17707, 2019 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31732685
15.
Increased mitochondrial apoptotic priming of human regulatory T cells after allogeneic hematopoietic stem cell transplantation.
Haematologica
; 99(9): 1499-508, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24859877
16.
BH3 profiling in whole cells by fluorimeter or FACS.
Methods
; 61(2): 156-64, 2013 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23607990
17.
HTRA1 disaggregates α-synuclein amyloid fibrils and converts them into non-toxic and seeding incompetent species.
Nat Commun
; 15(1): 2436, 2024 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38499535
18.
Acquired Multidrug Resistance in AML Is Caused by Low Apoptotic Priming in Relapsed Myeloblasts.
Blood Cancer Discov
; 5(3): 180-201, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38442309
19.
Prophylactic maintenance with venetoclax/azacitidine after reduced-intensity conditioning allogeneic transplant for high-risk MDS and AML.
Blood Adv
; 8(4): 978-990, 2024 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38197938
20.
Heightened mitochondrial priming is the basis for apoptotic hypersensitivity of CD4+ CD8+ thymocytes.
Proc Natl Acad Sci U S A
; 107(29): 12895-900, 2010 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-20615979